TABLE 1.
Multivariate logistic regression analysis of mitochondrial haplogroups associated with disability with adjustment for age, sex, and haplogroup.
| Haplogroups | Normal (n = 218) | Disability (n = 245) | OR (95% CI) | p-value |
| A | 17 (7.8%) | 18 (7.3%) | 1.26 (0.57–2.79) | 0.558 |
| B | 32 (14.7%) | 44 (18.0%) | 1.63 (0.87–3.05) | 0.125 |
| D4 | 47 (21.6%) | 41 (16.7%) | 1.0 | |
| D5 | 11 (5.0%) | 19 (7.8%) | 2.18 (0.91–5.19) | 0.077 |
| F | 37 (17.0%) | 40 (16.3%) | 1.27 (0.68–2.36) | 0.441 |
| G | 11 (5.0%) | 10 (4.1%) | 1.07 (0.41–2.81) | 0.886 |
| M7 | 8 (3.7%) | 27 (11.0%) | 3.90 (1.59–9.56) | 0.003 |
| M8 | 27 (12.4%) | 20 (8.2%) | 0.89 (0.43–1.84) | 0.769 |
| N9 | 11 (5.0%) | 11 (4.5%) | 1.14 (0.45–2.93) | 0.772 |
| Others* | 17 (7.7%) | 15 (6.1%) | – | – |
Values in parentheses are the percentage of samples. CI, confidence interval; OR, odds ratio. *represents haplogroup with frequencies <5% in normal and disability group. P < 0.005 (0.05/9), adjusted p-value with Bonferroni correction while 9 haplogroups studied in this study.