TABLE 4.

Comparison of different multi-omics integration algorithms with respect to methods and applications.

Algorithms	Methods	Applications
		Cancer subtyping	Cancer biomarker prediction	Cancer mechanisms
SNF	Network-based	+	–	–
iOmicsPASS	Network-based	+	+	+
iClusterPlus	Bayesian	+	+	+
PFA	Fusion-based	+	–	–
NEMO	Similarity-based	+	–	–
CCA	Correlation-based	–	–	+
moCluster	Multivariate analysis	+	-	–

SNF, Similarity network fusion; PFA, Pattern fusion analysis; NEMO, NEighborhood based multi-omics clustering; CCA, canonical correlation analysis; + indicates the appropriateness of the algorithm; – indicates the inappropriateness of the algorithm.