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Binding affinity (ΔG) predicted values for the interaction between spike and viral ACE2 receptor.
| Protein-protein complex (spike/Viral ACE2) | ΔG (kcal/mol) | SD |
| Chimpanzee | −50.7659 | ±11.7683 |
| Human | −46.7995 | ±14.6343 |
| Cat | −44.8766 | ±4.7180 |
| Cattle | −40.281 | ±5.5411 |
| Rhesus monkey | −39.326 | ±5.2482 |
| Dog | −37.7814 | ±7.2897 |
| Pig | −30.719 | ±6.5672 |
| Horse | −28.4732 | ±7.4204 |
| Sheep | −26.3634 | ±11.9568 |
| Mouse | −21.9914 | ±6.9997 |
| Rabbit | −16.749 | ±7.5223 |
