Table 2.

Individual and Multivariable Models of the Effect of Each Clinical Characteristic on the Rate of Change of SD-OCT RNFL Thickness Over Time

	Individual Effects Over Time
	Univariable Models		Multivariable Model
Characteristic	Coefficient	P	Coefficient	P
Diagnosis
Glaucoma suspect	0 (base)	–	0 (base)	–
Primary open-angle glaucoma	–0.109	<0.001	–0.266	<0.001
Other	–0.270	<0.001	–0.377	<0.001
Age at baseline, per 10 y older	–0.025	0.025	0.111	0.025
Sex, female	0.040	0.132	0.080	0.003
Race, black or African American	–0.005	0.862	–0.024	0.442
Years of follow-up	–0.020	0.003	–0.022	0.001
Baseline mean global RNFL thickness, per 10 µm thicker	–0.071	<0.001	–0.091	<0.001
CCT, per SD (40 µm) thinner	0.008	0.604	0.038	0.006
Average IOP during follow-up, per 1 mm Hg higher	–0.049	<0.001	0.013	0.519
Interaction term (age at baseline and average IOP during follow-up)	–	–	–0.010	0.001

Boldface indicates statistical significance (P < 0.05).