Table 2.
Clusters of decreased grey matter associated with lateral flexion of the trunk in PD.
| Region | Side | cluster size | T-values | MNI coordinates | ||
|---|---|---|---|---|---|---|
| (voxels) | x | y | z | |||
| trunk flexion (no flipping of scans) | ||||||
| Posterior parietal cortex | right | 1130 | ||||
| - Inferior parietal lobule/angular gyrus* | 6.24 | 56 | −62 | 32 | ||
| - Intraparietal sulcus | 5.70 | 39 | −50 | 40 | ||
| - Inferior parietal lobule | 4.89 | 54 | −58 | 45 | ||
| trunk flexion (right-left flipping of scans#) | ||||||
| Thalamus (ventral lateral nucleus)* | right | 379 | 5.92 | 20 | −20 | 18 |
| Temporoparietal cortex | left | 740 | ||||
| - Superior temporal gyrus/inferior parietal lobule | 5.67 | −54 | −40 | 15 | ||
| - Middle temporal gyrus | 5.25 | −64 | −34 | 3 | ||
| Posterior parietal cortex | right | 1076 | ||||
| - Inferior parietal lobule | 5.14 | 51 | −57 | 26 | ||
| - Intraparietal sulcus | 5.08 | 40 | −57 | 45 | ||
Legend: Voxel-based-morphometry findings (cluster-forming threshold < 0.001, FWE correction at the cluster-level) that correlated with lateral flexion of the trunk are reported. The respective clusters including local maxima are listed. The asterisk (*) indicates clusters significant at p < 0.05 after FWE correction on the peak and cluster-level. #Scans from patients who leant to the left side were right-left flipped as described in the methods section. Abbreviations: MNI = Montreal National Institute.