Figure 2. Hypothesized immunopathogenesis of sarcoidosis.
APC: antigen-presenting cell, HLA: human leukocyte antigen, BTNL2: butyrophilin-like 2, IL: interleukin, GM-CSF: granulocyte-macrophage colony-stimulating factor, MIP: macrophage inflammatory protein, MCP-1: monocyte chemoattractant protein-1, CD4+ T cell: cluster of differentiation 4 T cell, Th: helper T, INF-γ: interferon-gamma