Table 2. Chart comparison of ILOCA, SAOA, and SCAs.

ILOCA: Idiopathic late-onset cerebellar ataxia; SAOA: sporadic adult-onset ataxia of unknown etiology; SCAs: spinocerebellar ataxias (SCAs); MSA-C: multiple system atrophy – cerebellar type.

	ILOCA	SAOA	SCAs
Heritability	Idiopathic/ not defined	Non-hereditary	Mostly autosomal dominant
Progression	Slow progression	Slow progression	Slow progression
Survival	Normal life span	Unknown	Variable, there is a wide range of 68-80 years depending on the type of mutation.
Onset	41.1 ± 14.2 years	Starting around the age of 50 years	Variable, different mutations in distinct loci are associated with this variation.
Neurogenic orthostatic hypotension	Rarely occurs	Seen in more than 50% of patients as a part of mild autonomic dysfunction	Nonspecific information found
Urinary incontinence	Appears in the late phase of the disease but with less frequency than MSA-C	More than 50% of patients have it as a part of mild autonomic dysfunction.	Presents as a part of the symptoms; however, urinary frequency was the most common symptom followed by voiding difficulty.
Extrapyramidal dysfunctions	Rare	Cerebellar ataxia	Yes, in combination with pyramidal symptoms