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. 2020 Sep 20;17(17):2611–2621. doi: 10.7150/ijms.45723

Figure 1.

Figure 1

RD reduces HFD-induced obesity in mice. Chow- and HFD-fed mice were treated daily with sterile saline or RD by intragastric gavage for 12 weeks. (A) Body weight. (B) Body weight gain at week 12. (C) FBG at week 12. (D) Epididymal fat accumulation. (E) Representative images of hematoxylin and eosin (H&E)-stained epididymal adipose tissues. Scale bar, 100 µm; magnification, ✕200. (F) Adipocyte size in epididymal adipose tissues was determined using Image J software. (G) Food intake at week 12. (H) Serum TG. (I) Serum free fatty acid. Data are presented as mean ± SEM, n=12 mice per group. Statistical analysis was performed using two-way (panel A) or one-way (Except panels A and G) analysis of variance (ANOVA) followed by Bonferroni's post hoc test; Panel G was analyzed by unpaired t test. *p<0.05; **p<0.01; ***p<0.001; ****p<0.0001; ns, not statistically significant. In panel A, **p<0.01; ***p<0.001; ****p<0.0001 versus HFD; ##p<0.01; ###p<0.001; ####p<0.0001 versus chow.