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. 2020 Sep 23;17(17):2735–2743. doi: 10.7150/ijms.51329

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HCP5 knockdown inhibits proliferation and induces apoptosis of DLBCL cells. (A) OCI-LY7 and OCI-LY3 cells that were transfected with HCP5 shRNA or nontargeting (NT) shRNA were subjected to qRT-PCR for HCP5 expression. (B) CCK-8 assay indicated that the viability of DLBCL cells was significantly reduced by HCP5 shRNA. (C) HCP5 knockdown prominently induced the percentage of apoptotic DLBCL cells. (D) HCP5 silencing increased the levels of cleaved PARP and cleaved caspase-3 in DLBCL cells. *P<0.05.