Table 1.
Demographics of 160 islet autoantibody positive DAISY participants.
| Progressors | Non-Progressors | P | |
|---|---|---|---|
| N = 87 | N = 73 | ||
| FDR, N (%) | 62 (71.26) | 44 (60.27) | 0.14* |
| Female, N (%) | 45 (51.72) | 38 (52.05) | 0.97* |
| NHW, N (%) | 79 (90.8) | 50 (68.49) | 0.0004* |
| HLA DR 3/4, N (%) | 40 (45.98) | 22 (30.14) | 0.04* |
| HLA DR, N (%) | |||
| 3/4 | 40 (45.98) | 22 (30.14) | 0.047† |
| 3/3 or 3/X | 16 (18.39) | 13 (17.81) | |
| 4/4 or 4/X | 26 (29.89) | 25 (34.25) | |
| X/X | 5 (5.75) | 13 (17.81) | |
| Age at seroconversion | |||
| Mean (SD) | 3.64 (3.09) | 8.49 (4.98) | < 0.0001‡ |
| Time from seroconversion | |||
| Mean (SD) | 6.48 (4.73) | 10.89 (5.89) | < 0.0001‡ |
Age at seroconversion: age of participant at time of seroconversion to persistent positivity for an autoantibody detected by either RBA or ECL methodology.
Time from seroconversion: time to T1D or last visit.
FDR first degree relative, NHW non-Hispanic white.
*Chi-square.
†Fisher’s exact.
‡Wilcoxon Rank Sum Test.
p < 0.05.