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. 2020 Oct 28;48(10):0300060520962946. doi: 10.1177/0300060520962946

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© The Author(s) 2020

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Features of a novel mouse model of photoaging. A mouse model of skin photoaging was developed using UV irradiation combined with the photosensitizer, 8-methoxypsoralen. (a) Mouse body weight, (b) gross skin appearance, (c) wrinkle score, (d) hematoxylin and eosin staining, (e) dermal thickness, (f) Weigert staining, (g) elastic fiber score, (h) proliferating cell nuclear antigen, (i) proliferation index, and (j) matrix metalloproteinase 1 expression were evaluated in control and photoaging mice. P value compared with the NC group.

NC, normal control; M, photoaging model group; PI, proliferation index.