Table 3.
Pathway analysis of significantly differentiated genes in control group (non-filtered air) compared to PM2.5 group, and between PM2.5 and PM1 group. Experiment entities column denote the number of differentially expressed genes between each pairwise analysis and the pathway entities column denote the sum of the genes involved in each biochemical pathway. P-value < 0.05.
| Control – PM2.5 | |||
|---|---|---|---|
| Biological Pathway | P-value | Experiment entities | Pathway entities |
| 1. Rn_p38_MAPK_Signaling_Pathway_WP294_95743 | 0.019649707 | 1 | 34 |
| 2. Rn_Endochondral_Ossification_WP1308_107233 | 0.035450514 | 1 | 61 |
| 3. Rn_Thick_Ascending_Limb_Transporters_WP3882_106985 | 0.011359166 | 1 | 19 |
| 4. Rn_TNF-alpha_NF-kB_Signaling_Pathway_WP457_69441 | 0.09733374 | 1 | 175 |
| 5. Rn_Proximal_Tubule_Transporters_WP3881_94666 | 0.031960495 | 1 | 54 |
| PM2.5 – PM1 | |||
| Biological Pathway | P-value | Experiment entities | Pathway entities |
| 1. Rn_Endochondral_Ossification_WP1308_107233 | 0.017173307 | 1 | 61 |
| 2. Rn_TNF-alpha_NF kB_Signaling_Pathway_WP457_69441 | 0.04795735 | 1 | 175 |