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. 2020 Nov 5;10:19158. doi: 10.1038/s41598-020-76119-w

Table 1.

Alkaloid quantity in Kratom products.

Sample code Mitragynine (mg/g)b 7-Hydroxymitragynine (mg/g)b Speciofoline (mg/g)b
K50 11.37 ± 0.83 0.053 ± 0.014  < LOQc
K51 11.45 ± 0.74 0.056 ± 0.019  < LOQc
K52 8.13 ± 0.95 0.0349 ± 0.0030 4.13 ± 0.45
K55 0.75 ± 0.14  < LOQd  < LOQc

Samples K50, K51 and K52 are commercial kratom products that were purchased for this study. Sample K55 is a young cultivated kratom plant. Quantities were calculated by preparing methanolic extracts in triplicate and analyzing by LC–MS.

aQuantity is denoted as mg of compound per g of dried kratom plant material.

bUncertainty calculated using standard deviation of triplicate extractions, each analyzed separately.

cLimit of quantitation (LOQ) for speciofoline is 4.9 ng/mL (Table S3) and this sample contained speciofoline below that level.

dLOQ for 7-hydroxymitragynine is 0.49 ng/mL (Table S3) and this sample contained 7-hydroxymitragynine below that level.