Table 1.
Alkaloid quantity in Kratom products.
Sample code | Mitragynine (mg/g)b | 7-Hydroxymitragynine (mg/g)b | Speciofoline (mg/g)b |
---|---|---|---|
K50 | 11.37 ± 0.83 | 0.053 ± 0.014 | < LOQc |
K51 | 11.45 ± 0.74 | 0.056 ± 0.019 | < LOQc |
K52 | 8.13 ± 0.95 | 0.0349 ± 0.0030 | 4.13 ± 0.45 |
K55 | 0.75 ± 0.14 | < LOQd | < LOQc |
Samples K50, K51 and K52 are commercial kratom products that were purchased for this study. Sample K55 is a young cultivated kratom plant. Quantities were calculated by preparing methanolic extracts in triplicate and analyzing by LC–MS.
aQuantity is denoted as mg of compound per g of dried kratom plant material.
bUncertainty calculated using standard deviation of triplicate extractions, each analyzed separately.
cLimit of quantitation (LOQ) for speciofoline is 4.9 ng/mL (Table S3) and this sample contained speciofoline below that level.
dLOQ for 7-hydroxymitragynine is 0.49 ng/mL (Table S3) and this sample contained 7-hydroxymitragynine below that level.