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. 2020 Nov 4;40(13):1432–1442. doi: 10.1177/0333102420965146

Table 2.

Phenotypic ICHD-3 criteria C and D for 1.1 migraine without aura.

Criterion All patients (n = 106) No history of migraine (n = 88) Prior history of migraine (n = 18) Adjusted p-value
C. Headache has at least two of the following four characteristics
 Unilateral location 16 (15.1%) 8 (9.1%) 8 (44.4%) 0.004
 Pulsating quality 23 (21.7%) 20 (22.7%) 3 (16.7%) 1
 Moderate or severe pain intensity 102 (96.2%) 84 (95.5%) 18 (100%) 1
 Aggravation by or causing avoidance of routine physical activity 36 (34.0%) 25 (28.4%) 11 (61.1%) 0.133
 At least two: 55 (51.9%) 43 (48.9%) 12 (66.7%) 1
During the headache at least one of the following
 Nausea and/or vomiting 15 (14.2%) 12 (13.6%) 3 (16.7%) 1.000
 Photophobia and phonophobia 31 (29.2%) 23 (26.1%) 8 (44.4%) 1
 At least one 40 (37.7%) 31 (25.2%) 9 (50%) 1

ICHD-3: The International Classification of Headache Disorders, 3rd edition.