Table 1. Characteristics of Adult Women Who Had BRCA Test Results Noted in their Electronic Health Records in 2008-2018.
| Characteristic | Women, No. (%) [95% CI] | P valuea | ||
|---|---|---|---|---|
| Total (N = 5533) | No positive test result (n = 1502) | Positive test result (n = 4031) | ||
| Age, mean, y | 68.1 (67.9-68.4) | 68.5 (68.1-68.9) | 68.0 (67.7-68.3) | .05 |
| Race/ethnicityb | ||||
| Non-Hispanic White | 4679 (84.6) [83.6-85.5] | 1340 (89.2) [87.6-90.8] | 3339 (82.8) [81.7-84.0] | <.001 |
| Non-Hispanic Black | 273 (4.9) [4.4-5.5] | 45 (3.0) [2.1-3.9] | 228 (5.7) [4.9-6.4] | |
| Hispanic | 96 (1.7) [1.4-2.1] | 19 (1.3) [0.7-1.8] | 77 (1.9) [1.5-2.3] | |
| Regionc | ||||
| Northeast | 1132 (20.5) [19.4-21.5] | 407 (27.1) [24.8-29.3] | 725 (18.0) [16.8-19.2] | <.001 |
| West | 1403 (25.4) [24.2-26.5] | 161 (10.7) [9.2-12.3] | 1242 (30.8) [29.4-32.2] | |
| Midwest | 1915 (34.6) [33.4-35.9] | 708 (47.1) [44.6-49.7] | 1207 (29.9) [28.5-31.4] | |
| South | 989 (17.9) [16.9-18.9] | 198 (13.2) [11.5-14.9] | 791 (19.6) [18.4-20.8] | |
| Percentage with college educationc | 5439 (27.2) [26.9-27.4] | 422 (28.7) [28.2-29.1] | 1055 (26.6) [26.3-26.9] | <.001 |
| Annual household income ≥$50 000c | 5439 (24.2) [23.0-25.3] | 479 (32.5) [30.1-34.9] | 836 (21.1) [19.8-22.4] | <.001 |
| Family history of breast cancer | 5533 (34.1) [32.8-35.3] | 573 (38.1) [35.7-40.6] | 1312 (32.5) [31.1-34.0] | <.001 |
| Family history of ovarian cancer | 5533 (8.2) [7.5-8.9] | 117 (7.8) [6.4-9.1] | 337 (8.4) [7.5-9.2] | .49 |
| Personal history of breast cancer | 5533 (39.0) [37.8-40.3] | 685 (45.6) [43.1-48.1] | 1475 (36.6) [35.1-38.1] | <.001 |
| Personal history of ovarian cancer | 5533 (6.6) [5.9-7.2] | 93 (6.2) [5.0-7.4] | 270 (6.7) [5.9-7.5] | .50 |
a
The differences in characteristics between women with and women without pathogenic variants were assessed by the χ2 test, except for differences in mean age and percentage of college education, which were assessed by the Wald t test.
b
Race/ethnicity in the “Other” category was not reported (n = 322).
c
Region of residence in the “Unknown” category was not reported (n = 94). These participants also had missing values for “Percentage with college education” and “Annual household income ≥$50 000,” as the latter 2 variables were derived from zip code data.