Table 2. Multivariate Regression Models to Identify Risk Factors Associated With Brain Parenchymal Fraction Change.
| Follow-up | β (95% CI) | P value | Covariate R2 |
|---|---|---|---|
| 5 y (n = 117) | NA | NA | 0.17 |
| Intercept | 0.8045 (−0.1591 to 1.7682) | .10 | NA |
| log(baseline serum neurofilament light level) | −0.3586 (–0.5614 to –0.1558) | <.001 | 0.08 |
| log(T2 volume at baseline) | −0.1577 (–0.2855 to –0.0299) | .02 | 0.03 |
| 10 y (n = 65) | NA | NA | 0.17 |
| Intercept | −0.4096 (–1.5336 to 0.7145) | .48 | NA |
| log(baseline serum neurofilament light level) | −0.7902 (–1.2046 to –0.3758) | <.001 | NA |
Abbreviation: NA, not available.