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. 2020 Nov 5;10:19084. doi: 10.1038/s41598-020-76202-2

Table 2.

Gene Ontology (GO) categories with the lowest p values associated to DEG between LA and HA groups.

Name ID p value FDR Hit count
GO: biological process
1 Blood vessel development GO:0001568 4.40E−09 8.60E−06 24/849
2 Cellular response to cytokine stimulus GO:0001944 1.04E−08 8.60E−06 28/1188
3 Skeletal system development GO:0071345 2.25E−08 1.14E−05 19/582
4 Positive regulation of cell population proliferation GO:0048514 3.35E−08 1.32E−05 26/1096
5 Negative regulation of response to external stimulus GO:0072358 6.68E−08 1.97E−05 16/437
GO: cellular component
1 Extracellular matrix GO:0031012 3.83E−14 1.11E−11 26/59
2 Collagen-containing extracellular matrix GO:0062023 1.20E−12 1.73E−10 22/47
3 Clathrin-coated vesicle membrane GO:0030665 1.54E−05 1.49E−03 7/11
4 Collagen trimer GO:0005581 2.86E−05 2.06E−03 6/8
5 Cell surface GO:0009986 2.37E−04 1.34E−02 18/103
GO: molecular function
1 Receptor regulator activity GO:0030545 6.81E−08 1.07E−05 18/547
2 Sulphur compound binding GO:1901681 7.58E−07 8.81E−05 12/279
3 Integrin binding GO:0005178 1.02E−06 8.81E−05 9/146
4 Growth factor activity GO:0008083 3.12E−06 2.06E−04 9/167
5 N,N-dimethylaniline monooxygenase activity GO:0004499 3.49E−06 2.06E−04 3/5

FDR false discovery rate.