Table 2. Prevalence of Comorbid Infectious Conditions in Patients With Endogenous Endophthalmitis.

Comorbid infectious conditions	Patients with or without history of drug dependence or use
	No. (%)			P value	Raw difference (95% CI)
	All patients with endogenous endophthalmitis (n = 56 839)	History of drug dependence or use
		No (n = 49 056)	Yes (n = 7783)
Fungemia	1760 (3.1)	1399 (2.9)	361 (4.6)	<.001	−1.8 (−2.3 to −1.3)
Candida infection	3792 (6.7)	3030 (6.2)	762 (9.8)	<.001	−3.6 (−4.3 to −2.9)
Disseminated candidiasis	783 (1.4)	641 (1.3)	142 (1.8)	<.001	−0.5 (−0.8 to −0.2)
Aspergillus infection	252 (0.4)	223 (0.5)	29 (0.4)	.31	0.1 (−0.1 to 0.2)
Bacteremia	1890 (3.3)	1573 (3.2)	317 (4.1)	<.001	−0.9 (−1.3 to −0.4)
Sepsis	6423 (11.3)	5577 (11.4)	846 (10.9)	.20	0.6 (−0.3 to 1.3)
Osteomyelitis	1163 (2.0)	957 (2)	206 (2.6)	<.001	−0.7 (−1.1 to −0.3)
Infective endocarditis	2102 (3.7)	1651 (3.4)	451 (5.8)	<.001	−2.4 (−3.0 to −1.9)
Hepatic abscess	184 (0.3)	174 (0.4)	10 (0.1)	.001	0.2 (0.1 to 0.3)
Urinary tract infection	7628 (13.4)	6926 (14.1)	702 (9)	<.001	5.1 (4.4 to 5.8)
Intracranial and intraspinal abscess	509 (0.9)	392 (0.8)	117 (1.5)	<.001	−0.7 (−1.0 to −0.4)
Meningitis	422 (0.7)	333 (0.7)	89 (1.1)	<.001	−0.5 (−0.7 to −0.2)
Skin/soft tissue infection	5361 (9.4)	4433 (9)	928 (11.9)	<.001	−2.9 (−3.7 to −2.1)
Septic arthritis	640 (1.1)	586 (1.2)	54 (0.7)	<.001	0.6 (0.3 to 0.7)
Pneumonia	6164 (10.8)	5540 (11.3)	624 (8)	<.001	3.3 (2.6 to 3.9)
Gastrointestinal infection	2677 (4.7)	2280 (4.6)	397 (5.1)	.08	−0.5 (−1.0 to 0.1)
Peritoneal and retroperitoneal infections	442 (0.8)	369 (0.8)	73 (0.9)	.08	−0.2 (−0.4 to 0)
Orbital cellulitis and osteomyelitis	2566 (4.5)	2226 (4.5)	340 (4.4)	.50	0.2 (−0.3 to 0.7)
Hepatitis
Type B	282 (0.5)	198 (0.4)	84 (1.1)	<.001	−0.7 (−0.9 to −0.4)
Type C	1669 (2.9)	790 (1.6)	879 (11.3)	<.001	−9.7 (−10.4 to −9.0)
HIV infection	750 (1.3)	460 (0.9)	290 (3.7)	<.001	−2.8 (−3.2 to −2.4)