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. 2020 Nov 5;139(1):1–9. doi: 10.1001/jamaophthalmol.2020.4741

Table 3. Prevalence of Comorbid Noninfectious Conditions in Patients With Endogenous Endophthalmitis.

Comorbid noninfectious conditions Patients with or without history of drug dependence or use Raw difference (95% CI)
No. (%) P value
All patients with endogenous endophthalmitis (n = 56 839) History of drug dependence or use
No (n = 49 056) Yes (n = 7783)
Diabetes mellitus 15 690 (27.6) 13 958 (28.5) 1732 (22.3) <.001 6.2 (5.2 to 7.2)
Chronic kidney disease 8058 (14.2) 7354 (15.0) 704 (9.0) <.001 6.0 (5.2 to 6.7)
Malignancy 10 938 (19.2) 9740 (19.9) 1198 (15.4) <.001 4.5 (3.6 to 5.3)
Organ or tissue transplant 1152 (2.0) 1039 (2.1) 113 (1.5) <.001 0.7 (0.4 to 1.0)
Neutropenia 691 (1.2) 653 (1.3) 38 (0.5) <.001 0.8 (0.7 to 1.0)
Immunodeficiency diseases 1695 (3.0) 1361 (2.8) 334 (4.3) <.001 −1.5 (−2.0 to −1.0)
Liver cirrhosis 1097 (1.9) 844 (1.7) 253 (3.3) <.001 −1.5 (−1.9 to −1.1)
COPD/asthma 5760 (10.1) 4569 (9.3) 1191 (15.3) <.001 −6.0 (−6.8 to −5.2)
Drug dependence or use 7783 (13.7) 0 7783 (100) NA NA
Mortality 1903 (3.4) 1766 (3.6) 137 (1.8) <.001 1.8 (1.5 to 2.2)

Abbreviation: NA, not applicable.