Table 1.

Summary of differences between male and female TDP-43^Q331K mice in age of onset of behavioural phenotypes, compared to wild-type.

Phenotype (compared to wild-type)	Age of onset (months)
	Male23	Female
Weight gain	8	13
Increased food intake	9a	20b
Reduced marble burying	5	14b
Gait defects	6	20
Reduced running	n/ac	8
Muscle denervation	None	None

^aEarliest age at which food intake was measured.

^bStatistical trend.

^cAs male mice on the C57BL/6 background have low baseline levels for this task⁶⁹.