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. 2020 Nov 5;10:19097. doi: 10.1038/s41598-020-76200-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Examples of significant differences between clusters with respect to clinical baseline features in PD patients after correction for confounding effects (see “Methods” section). (A) MDS-UPDRS I score (AETIONOMY PD); (B) MDS-UPDRS III on treatment score (ICEBERG); (C) HADS anxiety score (ICEBERG); (D) Schwab-England Scale in % (AETIONOMY PD). The Figures shows statistical distributions as violin plots (i.e. boxplots plus kernel density estimates), and individual data points are shown as superimposed dots.