Figure 1.

Cellular injury in the lung of COVID‐19 patients. A, Serum levels of SPD, RAGE, laminin and vWF were measured in healthy subjects, COVID‐19 patients at acute infection stage (9‐14 days after SARS‐CoV‐2 infection) and COVID‐19 patients at recovery stage (14 days after SARS‐CoV‐2 clearance) by ELISA. B, Levels of injury markers in 14 patients at acute infection stage and recovery stage. C, Levels of injury markers in male moderate and severe patients at acute infection stage and recovery stage. D, Levels of injury markers in female moderate and severe patients at acute infection stage and recovery stage. Data represent the median ± SD P values were determined with unpaired, two‐sided Mann‐Whitney U test. *P < .05; **P < .01; ****P < .0001. All statistical analyses were performed using SPSS version 19.0 software