FIGURE 1.

The epithelial cell landscape in the BALF of COVID‐19 patients. A, The UMAP presentation of the heterogeneous clusters of BALF epithelial cells (all individuals combined, n = 13). B, Comparison of UMAP projection of 8 epithelial clusters among healthy controls (HC, n = 4) and severe COVID‐19 patients (S, n = 6). C, Comparison of the major BALF epithelial cell type proportions in healthy controls (HC), patients with moderate (M) and severe (S) COVID‐19 infection. P‐values were indicated by numbers. **P < .01. D, The bar plot shows the percentage of epithelial cell clusters in each individual. E, The gene expression levels of selected alveolar markers in Cluster 6 from healthy controls (HC, n = 4), moderate cases (M, n = 3) and severe cases (S, n = 6). *P < .05, **P < .01. P‐value adjusted by false discovery rate in MAST