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. 2020 Sep 16;120(19):11093–11139. doi: 10.1021/acs.chemrev.0c00342

Table 3. Overview of Commercially Available Bionks for 3D Bioprinting.

bioink material type of cross-linking
RegenHU Ltd.
ECM-Bioink self-assembly peptides self-assembly
BiogelX
Biogelx-INK-S self-assembly peptides self-assembly
        
Biogelx-INK-RGD self-assembly peptides functionalized with biorelevant peptide sequences self-assembly
Biogelx-INK-GFOGER    
Manchester BIOGEL
PeptiInk series alpha 1: self-assembly peptides (neutral charge) self-assembly
  alpha 2: self-assembly peptides (charged) self-assembly
  alpha 4: self-assembly peptides (charged) self-assembly
Bioink Solutions Inc.
Gel4Cell GelMA UV cross-linking
        
Gel4Cell-peptide GelMA functionalized with growth factors mimetic peptides UV cross-linking
Cellink Life Sciences
A Series alginate (CELLINK A) ionic gelation
  RGD-functionalized alginate (CELLINK A-RGD)  
        
CELLINK series alginate and nanofibrillar cellulose (CELLINK), CELLINK supplemented with fibrinogen (CELLINK FIBRIN and CELLINK SKIN), laminin (CELLINK LAMININ), and CELLINK in which the alginate was functionalized with RGD (CELLINK RGD) ionic gelation or Ionic gelation/thrombin (in the case of bioinks supplemented with fibrinogen)
        
collagen series collagen type 1 (Coll 1) or collagen methacrylate (ColMA) self-assembly (Coll 1) and self-assembly followed by UV cross-linking (ColMA)
        
GelMA series GelMA and carbon nanotubes (Bio Conductink) photo-cross-linking (LAP photoinitiator)
  GelMA photo-cross-linking (LAP photoinitiator)
  GelMA and alginate (GelMA A) photo-cross-linking (LAP photoinitiator), followed by ionic gelation
  GelMA and CELLINK (GelMA C) photo-cross-linking (LAP photoinitiator), followed by ionic gelation
  GelMA with methacrylated hyaluronic acid (GelMA HA) photo-cross-linking (LAP photoinitiator)
  solution of GelMA with high concentration (GelMA HIGH) photo-cross-linking (LAP photoinitiator)
        
GelX series GelMA, xanthan gum, and alginate (GelXA) photo-cross-linking (LAP photoinitiator) and ionic gelation
  GelMA, xanthan gum, alginate, tricalcium phosphate, and hydroxyapatite (GelXA BONE) photo-cross-linking (LAP photoinitiator) and ionic gelation
  GelMA, xanthan gum, alginate, and fibrinogen (GelXA FIBRIN) photo-cross-linking (LAP photoinitiator), ionic gelation and thrombin
  GelMA, xanthan gum, alginate, and various laminins (GelXA LAMININ) photo-cross-linking (LAP photoinitiator) and ionic gelation
  GelMA, xanthan gum, alginate, and fibrinogen (GelXA SKIN) photo-cross-linking (LAP photoinitiator), ionic gelation and thrombin
  GelMA, xanthan gum (GelXG) photo-cross-linking (LAP photoinitiator)
Advanced Biomatrix
LifeInk series collagen type 1 (LifeInk 200) self-assembly
  acidified collagen type 1 (LifeInk240) self-assembly
        
PhotoCol series ColMA (PhotoCol) photo-cross-linking
  ColMA + Irgacure (PhotoCol-IRG) UV cross-linking (365 nm)
  ColMA + LAP photoinitiator (PhotoCol-LAP) blue light mediated cross-linking (405 nm)
  ColMA + ruthenium photoinitiator (PhotoCol-RUT) visible light mediated cross-linking (400–450 nm)
        
PhotoGel series GelMA (PhotoGel) photo-cross-linking
  GelMA + Irgacure (PhotoGel-IRG) UV cross-linking (365 nm)
  GelMA + LAP photoinitiator (PhotoGel-LAP) blue light mediated cross-linking (405 nm)
  GelMA + ruthenium photoinitiator (PhotoGel-RUT) visible light mediated cross-linking (400–450 nm)
        
PhotoHA series HAMA (PhotoHA) photo-cross-linking
  HAMA + Irgacure (PhotoHA-IRG) UV cross-linking (365 nm)
  HAMA + LAP photoinitiator (PhotoHA-LAP) blue light mediated cross-linking (405 nm)
  HAMA + ruthenium photoinitiator (PhotoHA-RUT) visible light mediated cross-linking (400–450 nm)
        
HyStem series thiolated HA (HA-SH) and PEGDA (HyStem ) Michael addition
  HA-SH, PEGDA, and thiolated gelatin (HyStem-C) Michael addition
  HA-SH, PEGDA, thiolated gelatin and thiolated heparin (HyStem-HP) Michael addition
  HA-SH, thiolated gelatin, PEG-norbornene Michael addition mediated by UV photo-cross-linking (365 nm)
UPM Biomedicals
GrowInk nanofibrillar cellulose (GrowInk-N) self-assembly
  anionic nanofibrillar cellulose (GrowInk-T) self-assembly (with possibility of postcross-linking)
  nanofibrillar cellulose with alginate (GrowInk-ALG) self-assembly and ionic cross-linking