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. 2020 Oct 23;16(16):3221–3230. doi: 10.7150/ijbs.49410

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GRB7 promotes the tumorigenesis of bladder cancer. A. Representative images from the anchorage-independent growth assay show that the colony number was significantly increased in exogenous GRB7-overexpressed cells but decreased in endogenous GRB7-silenced cells. B. The mean count of the colony number in the anchorage-independent growth assay. C. Images of excised tumors from NOD/SCID mice which injection with 5637-Vector, 5637-GRB7, 5637-RNAi vector, 5638-RNAi1 or 5637-RNAi2 cells. D. Tumor volumes were measured every 4 days. Data represent the mean ± SD of three independent measures. E. Average weight of excised tumors from three different weighing instruments. *P < 0.05.