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. 2020 Nov 5;25:69. doi: 10.1186/s12199-020-00910-4

Table 3.

Odds ratios (ORs) and 95% confidence intervals (CIs) for hypertension in relation to thyroid stimulating hormone (TSH)

Thyroid stimulating hormone (TSH) p TSH (logarithmic values)
T1 (low) T2 (medium) T3 (high)
Total
 Number at risk 571 579 574
 Number of case 200 (35.0) 231 (39.9) 255 (44.4)
 Model 1 1 1.22 (0.95, 1.59) 1.34 (1.03, 1.73) 0.029 1.23 (1.03, 1.47)
 Model 2 1 1.23 (0.95, 1.59) 1.35 (1.04, 1.75) 0.024 1.24 (1.04, 1.48)
 Model 3 1 1.15 (0.88, 1.51) 1.15 (0.87, 1.51) 0.324 1.10 (0.91, 1.33)
Thyroid cyst (-)
 Number at risk 376 395 389
 Number of case 117 (31.1) 143 (36.2) 174 (44.7)
 Model 1 1 1.26 (0.91, 1.75) 1.62 (1.17, 2.24) 0.003 1.42 (1.14, 1.78)
 Model 2 1 1.27 (0.92, 1.76) 1.64 (1.19, 2.28) 0.003 1.44 (1.15, 1.81)
 Model 3 1 1.18 (0.83, 1.66) 1.37 (0.97, 1.95) 0.075 1.27 (1.01, 1.61)
Thyroid cyst (+)
 Number at risk 195 184 185
 Number of case 83 (42.6) 88 (47.8) 81 (43.8)
 Model 1 1 1.19 (0.78, 1.84) 0.94 (0.61, 1.45) 0.794 0.94 (0.70, 1.27)
 Model 2 1 1.19 (0.78, 1.84) 0.95 (0.62, 1.45) 0.804 0.95 (0.70, 1.28)
 Model 3 1 1.13 (0.71, 1.77) 0.78 (0.49, 1.24) 0.306 0.79 (0.57, 1.09)

Model 1: adjusted for sex and age. Model 2: + free T3. Model 3: + BMI, smoking status, drinking status, TG, HDLc and HbA1c. Tertile values of TSH for men and women are <1.21 μIU/ml and <1.26 μIU/ml for T1 (low), 1.21-1.89 μIU/ml and 1.26-2.08 μIU/ml for T2 (medium), and 1.90 μIU/ml ≤ and 2.09 μIU/ml ≤ for T3 (high). Case: hypertension. TSH (logarithmic values): ORs and 95% CIs for hypertension in relation to logarithmic values of TSH. ORs and 95% CIs are calculated by logistic regression models.