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. 2020 Aug 12;18(2):104–119. doi: 10.1016/j.gpb.2019.11.008

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© 2020 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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DIA analysis of plasma samples from DLBCL patients and HC subjects

A. Technical reproducibility for protein quantification of four plasma samples from two DLBCL patients and two healthy control subjects. B. 2D plane t-SNE plot showing that proteomes are separated. C. Volcano plot showing significantly down-regulated (blue) and up-regulated (red) proteins in 37 plasma samples (19 samples from DLBCL patients and 18 samples from HC subjects). D. The relative protein expression as calculated by MS intensity for CRP and SAA1. P values adjusted with Benjamini & Hochberg are shown under each protein name Left: Boxplot and ROC curve of CRP. Right: Boxplot and ROC curve of SAA1. DLBCL, diffuse large B cell lymphoma; HC, healthy control; CRP, C-reactive protein, UniProtKB: P02741; SAA1, serum amyloid A1, UniProtKB: P0DJI8.