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Effect of naringenin treatment on ERK1/2 and JNK MAPKs signaling. (A-D) Images and quantification of protein expression of p-ERK1/2 and p-JNK in B16F10 (A, B) and SK-MEL-28 cells (C, D) after naringenin treatment in a dose-dependent manner. Values are mean ± SD from ≥ three independent experiments. *p = 0.0265, **p< 0.0071, ***p= 0.0006; ##p = 0.0013, ###p = 0.0002 versus untreated cells by one-way ANOVA followed by Bonferroni post-tests.
