Table 2.
Characterization and clinical outcomes of heart, liver, and lung transplant recipients with COVID-19
| Patient Age and Gender) | Organ (years) |
ISx History | Comorbidity | Symptoms on Admission | ISx Used in Hospital | Other Medicines used in Hospital | In-Hospital Complications | ICU/Vent | Length of Hospital Stay (days) | Clinical Outcome | Ref. |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 59 (F) | Heart(8) | TAC MMF |
HPN DM CKD |
Cough, fever, dyspnea | TAC (removed on day 6) MMF |
HCQ, tocilizumab, IVIG, lopinavir, ritonavir, antibiotics | ARDS, Renal failure |
Y/Y | 10 | Death | 25 |
| 63 (M) | Heart(17.9) | Pred Cysp MMF | HPN DM CVD CKD Cancer |
Cough, fever, dyspnea | Pred MMF |
HCQ, lopinavir, ritonavir, interferon-beta | ARDS | */N | 10 | Death | 26 |
| 75 (M) | Heart(20) | Cysp MMF | HPN DM CKD CVD |
Cough, fever | Cysp | HCQ, tocilizumab, methylprednisolone | N/N | 8 | Discharged | 25 | |
| 51 (M) | Heart(17) | TAC MMF | HPN | Fever | Discontinued during the first 11 days and then resumed | moxifloxacin, ganciclovir, IVIG, methylprednisolone, arbidol | N/N | 33 | Discharged | 27 | |
| 77 (M) | Heart(17) | SIR MMF | HPN DM CVD CKD |
Cough, dyspnea | TAC | HCQ, piperacillin, tazobactam, cotrimoxzole, gancyclovir | ARDS | Y/N | 12 | Discharged | 28 |
| 67 (M) | Heart(10) | Pred Cysp MMF | HPN | Cough, fever | Pred (R.D.) MMF |
HCQ, lopinavir, ritonavir | */N | 23 | Discharged | 29 | |
| 38 (M) | Heart(8.7) | TAC MMF Pred | Cough, fever | Pred | HCQ | */N | 21 | Discharged | 29 | ||
| 43 (M) | Heart(3) | TAC MMF | HPL | Fever | Not reported | ceftriaxone, ganciclovir, moxifloxacin, arbidol | N/N | 7 | Discharged | 27 | |
| 74 (M) | Heart(23) | TAC, MAM | Cancer UC CVA OSA |
Cough, fever | Not reported | N/N | NA | Outpatient | 30 | ||
| 39 (M) | Heart and Kidney(3) | TAC MMF Pred | HPN DM |
Cough, fever, dyspnea | TAC Pred |
HCQ | Y/N | 10 | Discharged | 31 | |
| 72 (M) | Liver(5.5) | MMF EVE | HPN DM |
Cough, fever, dyspnea | TAC | HCQ, lopinavir, ritonavir, interferon-beta | ARDS | */N | 7 | Death | 26 |
| 73 (F) | Liver (16.4) | MMF | DM COPD |
Cough, fever, dyspnea | ARDS | Y/Y | 24 | Death | 26 | ||
| 59 (M) | Liver (3) | TAC MMF | Hep B | Cough, fever, dyspnea | TAC MMF (R.D.) |
interferon-alpha, lopinavir, ritonavir, piperacillin, tazobactam, methylprednisone, cefperazone-sulbactam, caspofungin, meropenem, coriconazole, IVIG | PNA, cholestasis | Y/Y | 45 | Death | 26 |
| 63 (M) | Liver (7.9) | EVE | HPN DM |
Cough, fever, dyspnea | TAC MMF |
*/N | 15 | Discharged | 26 | ||
| 79 (M) | Liver (15.3) | Pred EVE AZA |
DM CKD |
Cough, dyspnea | Pred EVE AZA |
HCQ, interferon-beta | */N | 14 | Discharged | 26 | |
| 63 (M) | Liver (10) | TAC | HPN DM CVD CKD Cancer Hep C |
Cough, fever, dyspnea | TAC | HCQ, ceftriaxone, azithromycin, vancomycin, cefepime, tocilizumab | N/N | 16 | Discharged | 32 | |
| 50 (M) | Liver (3) | TAC | Hep B | Fever | methylprednisone, interferon-alpha, cefoperazone, IVIG, umifenovir, lopinavir, ritonavir | N/N | 30 | Discharged | 33 | ||
| 67 (M) | Liver(19) | Cysp | Cysp | N/N | 6 | Discharged | 30 | ||||
| 64 (F) | Liver(13.8) | Pred Cysp MMF | IBD PSC |
Cough, fever, dyspnea | Pred (R.D.) MMF |
HCQ | ARDS | Y/Y | 21 | Remain in Hospital | 29 |
| 76 (M) | Liver(26.5) | TAC | HPN | Fever | TAC | HCQ | N/N | NA | Outpatient | 29 | |
| 46 (F) | Liver(6.4) | TAC | TAC | N/N | NA | Outpatient | 29 | ||||
| 53 (F) | Lung(20) | Cysp AZA Pred | CVD CKD |
Cough, dyspnea | Cysp AZA Pred |
N/N | NA | Outpatient | 30 | ||
| 59 (F) | Lung (1) | TAC Pred | Cough, dyspnea | No changes | trimethoprim, sulfamethoxazole, metamizole, salbutamol, merpenem |
N/N | 21 | Discharged | 34 | ||
*ICU care was not explicitly mentioned.
Abbreviations. ARDS: acute respiratory distress syndrome; AZA: azathioprine; CKD: chronic kidney disease; COPD: chronic obstructive pulmonary disease; CVA: cerebrovascular accident; CVD: cardiovascular disease; Cysp: cyclosporine; EVE: everolimus; HCQ: hydroxychloroquine; HPL: hyperlipidemia; HPN: hypertension; IBD: inflammatory bowel disease; ICU: Intensive care unit; MMF: mycophenolate mofetil; ISx: immunosuppressant; OP: outpatient; OSA: obstructive sleep apnea; Pred: prednisone; PNA: pulmonary nodular amyloidosis; PSC: primary sclerotic cholangitis; R.D.: reduced dose; SIR: Sirolimus; TAC: tacrolimus; UC: ulcerative colitis; Vent: ventilation.