Table 4.
Clinical and pathologic characteristics according to the depth of stromal invasion groups among patients with isolated inter-mediate risk factors
| Variable | Patients (%) | Subcategorization of DSI | P value | ||
|---|---|---|---|---|---|
| Total = 2105 | < full-thickness (n=1459, 69.3%) | full-thickness (n=594, 28.2%) | > full-thickness (n=52, 2.5%) | ||
| Mean age (years) | 47.8 (ranging 19 - 80) | 46.8 (ranging 19 - 80) | 49.9 (ranging 23 - 79) | 51.6 (ranging 33 - 74) | < 0.001 |
| Histologic type | 0.291 | ||||
| Squamous carcinoma | 1906 (90.5%) | 1314 (90.1%) | 541 (91.1%) | 51 (98.1%) | |
| Adenocarcinoma | 130 (6.2%) | 93 (6.2%) | 37 (6.2%) | 0 (0) | |
| Adenosquamous carcinoma | 69 (3.3%) | 52 (3.6%) | 16 (2.7%) | 1 (1.9%) | |
| FIGO stage (2009) | < 0.001 | ||||
| IB1 | 851 (40.4%) | 688 (47.2%) | 154 (25.9%) | 9 (17.3%) | |
| IB2 | 184 (8.7%) | 129 (8.8%) | 52 (8.8%) | 3 (5.8%) | |
| IIA1 | 760 (36.1%) | 478 (32.8%) | 253 (42.6%) | 29 (55.8%) | |
| IIA2 | 310 (14.7%) | 164 (11.2%) | 135 (22.7%) | 11 (21.2%) | |
| Menopause status | < 0.001 | ||||
| Menopause | 732 (34.8%) | 451 (30.9%) | 253 (42.6%) | 28 (53.8%) | |
| Premenopause | 1373 (65.2%) | 1008 (69.1%) | 341 (57.4%) | 24 (46.2%) | |
| Parity | 0.175 | ||||
| Yes | 87 (4.1%) | 68 (4.7%) | 18 (3.0%) | 1 (1.9%) | |
| No | 2018 (95.9%) | 1391 (95.3%) | 576 (97.0%) | 51 (98.1%) | |
| Mean tumor diameter (cm) | 3.8 (ranging 0.4 - 12.0) | 3.6 (ranging 0.4 - 12.0) | 4.3 (ranging 1.4 - 11.0) | 3.9 (ranging 1.1 - 6.5) | 0.023 |
| Lymphovascular space invasion | 0.034 | ||||
| Yes | 611 (29.0%) | 402 (27.6%) | 188 (31.6%) | 21 (40.4%) | |
| No | 1494 (71.0%) | 1057 (72.4%) | 406 (68.4%) | 31 (59.6%) | |
| Recurrent region | 0.454 | ||||
| Only pelvic | 95 (38.0%) | 62 (41.1%) | 28 (31.8%) | 5 (45.5%) | |
| Only extrapelvic | 134 (53.6%) | 75 (49.7%) | 53 (60.2%) | 6 (54.5%) | |
| Pelvic + extrapelvic | 21 (8.4%) | 14 (9.3%) | 7 (8.0%) | 0 (0) | |