Table 1. Watershed and CADD as predictors of variant effect size percentile.
Shown are the coefficient estimates and 95% confidence intervals from separate linear models with variant effect size percentile as the response and CADD score or Watershed posterior (scaled to have a mean of 0 and an SD of 1 so that values are of comparable range) as the predictor for all tested variants in colocalized regions (n = 5277).
| Predictor | Beta | P value | 95% confidence interval |
|---|---|---|---|
| Watershed posterior | 1.61 | 2.12 × 10−6 | 0.95–2.27 |
| CADD score | 0.77 | 2.41 × 10−2 | 0.10–1.43 |