Table 3. The comparison of clinical characteristics between normo-uricemia group and hyperuricemia group.
| Parameters | Normo-uricemia | Hyperuricemia | P |
|---|---|---|---|
| Patients(n) | 138 | 70 | – |
| Gender (male/female) | 46/92 | 36/34 | 0.012 |
| Age (years) | 33.7 ± 10.5 | 34.2 ± 11.2 | 0.7311 |
| Body weight (kg) | 59.7 ± 9.3 | 64.8 ± 12.9 | 0.0057 |
| MAP (mm Hg) | 91.8 ± 10.7 | 98.2 ± 12.5 | 0.0002 |
| White blood cells (*10°9/l) | 7.04 ± 1.85 | 7.55 ± 2.44 | 0.1248 |
| Hemoglobin (g/l) | 129.60 ± 16.75 | 130.30 ± 23.52 | 0.8214 |
| Platelet (*109/l) | 237.50 ± 62.07 | 239.10 ± 70.38 | 0.8704 |
| APTT(s) | 37.43 ± 3.66 | 37.57 ± 3.23 | 0.7833 |
| FDP (mg/l) | 3.23 ± 0.74 | 3.86 ± 1.38 | 0.0006 |
| Total protein(g/l) | 68.84 ± 7.08 | 67.80 ± 8.40 | 0.3497 |
| Albumin(g/l) | 40.03 ± 4.94 | 38.40 ± 7.05 | 0.0868 |
| Total cholesterol(mmol/l) | 4.53 ± 1.17 | 5.01 ± 1.55 | 0.0260 |
| Triglyceride(mmol/l) | 1.63 ± 1.02 | 2.54 ± 1.89 | 0.0005 |
| HDL-cholesterol (mmol/l) | 1.34 ± 0.49 | 1.14 ± 0.35 | 0.0056 |
| LDL-cholesterol (mmol/l) | 2.73 ± 0.95 | 3.03 ± 1.41 | 0.1606 |
| Uric acid (µmol/l) | 290.00 ± 66.27 | 462.40 ± 83.46 | <0.0001 |
| Blood urea nitrogen (mmol/l) | 5.12 ± 1.52 | 6.49 ± 1.95 | <0.0001 |
| Serum creatinine (µmol/l) | 80.40 ± 40.58 | 109.00 ± 36.54 | <0.0001 |
| eGFR (ml/min per 1.73mm2) | 98.98 ± 25.12 | 74.50 ± 29.52 | <0.0001 |
| 24-hour urine protein (g/d) | 1.05 ± 1.27 | 1.81 ± 1.67 | 0.0015 |
| IgA(g/l) | 3.22 ± 1.15 | 3.11 ± 1.00 | 0.5328 |
| IgG(g/l) | 2.91 ± 0.26 | 2.95 ± 0.38 | 0.1506 |
| IgM(g/l) | 1.56 ± 1.19 | 1.42 ± 0.67 | 0.3222 |
| C3(g/l) | 0.90 ± 0.22 | 1.00 ± 0.24 | 0.0055 |
| C4(g/l) | 0.20 ± 0.07 | 0.25 ± 0.12 | 0.0030 |
Notes.
MAP, mean arterial pressure; APTT, activated partial thromboplastin time; FDP, fibrin degradation products. eGFR was calculated with the CKD-EPI equation. Bold P-values indicate a statistical significance of P < 0.05.