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. 2020 Nov 3;8:e10281. doi: 10.7717/peerj.10281

Table 3. Gene sets enriched in POLR3G high expression phenotype.

Gene set NES NOM P value FDR q value
IL6 JAK STAT3 signaling 2.83 <0.001 <0.001
Allograft rejection 2.72 <0.001 <0.001
mTORC1 signaling 2.7 <0.001 <0.001
Protein secretion 2.69 <0.001 <0.001
Inflammatory response 2.67 <0.001 <0.001
Glycolysis 2.58 <0.001 <0.001
Heme metabolism 2.56 <0.001 <0.001
Mitotic spindle 2.53 <0.001 <0.001
Androgen response 2.46 <0.001 <0.001
Interferon-γ response 2.46 <0.001 <0.001
TNF-α signaling via NF-kB 2.44 <0.001 <0.001
PI3K AKT mTOR signaling 2.42 <0.001 <0.001
G2M checkpoint 2.36 <0.001 <0.001
Hypoxia 2.34 <0.001 <0.001
UV response down 2.32 <0.001 <0.001
Apical junction 2.28 <0.001 <0.001
Kras signaling up 2.28 <0.001 <0.001
Complement 2.28 <0.001 <0.001
Myc targets v1 2.22 <0.001 <0.001
Unfolded protein response 2.18 <0.001 0.006
UV response up 2.08 <0.001 0.011
IL2 STAT5 signaling 2.06 <0.001 0.015
Interferon-α response 2.03 <0.001 0.014
Epithelial mesenchymal transition 2.03 <0.001 0.014
E2F targets 2.03 <0.001 0.013
Apoptosis 2.02 <0.001 0.013
TGF-β signaling 2.02 <0.001 0.012
Adipogenesis 2 <0.001 0.012
Coagulation 1.96 <0.001 0.015
Reactive oxygen species pathway 1.88 <0.001 0.026
P53 pathway 1.87 <0.001 0.03
Fatty acid metabolism 1.87 <0.001 0.029
Estrogen response early 1.84 <0.001 0.028
Myc targets v2 1.83 <0.001 0.027
DNA repair 1.77 <0.001 0.035
Oxidative phosphorylation 1.77 <0.001 0.034
Angiogenesis 1.66 <0.001 0.056
Apical surface 1.62 <0.001 0.057
Spermatogenesis 1.59 <0.001 0.065
Estrogen response late 1.57 <0.001 0.076
Cholesterol homeostasis 1.46 <0.001 0.087

Notes.

NES
normalized enrichment score
NOM P value
nominal P value
FDR
false discovery rate