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. Author manuscript; available in PMC: 2020 Nov 6.
Published in final edited form as: J Pain Symptom Manage. 2018 Aug 8;56(5):727–735. doi: 10.1016/j.jpainsymman.2018.07.021

Table 4.

Unadjusted and adjusted means of symptom outcomes by trial arm and time period.

Unadjusted Adjusted
Experimental Arm Mean (SE) Control Arm Mean (SE) 95% CI for trial arm difference P-value Experimental Arm Mean (SE) Control Arm Mean (SE) 95% CI for trial arm difference P-value
Week 4
Number of symptoms above threshold 2.58 (0.28) 3.04 (0.29) (−1.26, 0.34) 0.26 2.46 (0.24) 2.84 (0.24) (−0.97,0.21) 0.21
Summed symptom severity 20.51 (1.98) 22.86 (1.94) (−7.82, 3.11) 0.40 19.26 (1.57) 21.74 (1.60) (−6.02,1.83) 0.21
Week 8
Number of symptoms above threshold 1.88 (0.23) 2.83 (0.26) (−1.63, −0.26) <.01 1.91 (0.24) 2.72 (0.24) (−1.41,−0.19) 0.01
Summed symptom severity 14.56 (1.38) 20.93 (1.70) (−10.70, −2.04) <.01 14.62 (1.65) 20.20 (1.65) (−9.53,−1.38) <.01
Week 12
Number of symptoms above threshold 2.18 (0.28) 2.36 (0.25) (−0.91, 0.56) 0.64 1.94 (0.24) 2.35 (0.24) (−1.02,0.21) 0.19
Summed symptom severity 16.70 (1.79) 17.35 (1.55) (−5.32, 4.03) 0.78 14.98 (1.63) 17.47 (1.63) (−6.75,1.40) 0.22