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. 2020 Nov 2;13:11193–11209. doi: 10.2147/OTT.S274092

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© 2020 Zheng et al.

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Expression of CTHRC1 in ESCC and its correlation with let-7c-5p. (A) Higher mRNA expression of CTHRC1 in 50 pairs of ESCC tissues compared to adjacent normal tissues by qRT-PCR. (B) Higher mRNA expression of CTHRC1 in five ESCC cell lines (TE-1, TE-10, TE-11, KYSE140 and KYSE150) compared to Het-1A by qRT-PCR. (C) Higher protein expression of CTHRC1 in ESCC tissues compared to adjacent noncancerous tissues by Western blot. (D) Higher protein expression of CTHRC1 in TE-1 and KYSE150 cells compared to Het-1A by Western blot. (E) Negative correlation between CTHRC1 and let-7c-5p in ESCC tissues. Statistical analysis was performed with Pearson’s correlation analysis (r =−0.418; p = 0.009). All results are shown as the mean ± SD of three separate experiments (n=3) **p < 0.01.