Table 6.

Reduction in Pharmacologic Glaucoma Medication – Summary of Studies

Study	No. of IOP-Lowering Agents at Baseline	No. of IOP-Lowering Agents 12 Months Postop	N	Glaucoma Type	Procedurea
De Gregorio et al,15 2018	2.5	0.4	41	Mixed cases	Combined
Gillmann et al,10 2019	1.9 2.0	0.6 0.4	110	POAG PEXG	Stand-alone and combined
Grover et al,7 2017	3.5	1.7	65	Mixed cases	Stand-alone
Hengerer et al,16 2017	3.13	0.3	242	Mixed cases	Stand-alone and combined
Mansouri et al,9 2018	1.9 2.0	0.4 0.5	110	POAG PEXG	Stand-alone and combined
Tan et al,12 2018	3.0	0.7	39	Mixed cases	Stand-alone
Widder et al,17 2018	2.6	0.2	233	Mixed cases	Stand-alone and combined

Notes: ^aStand-alone XEN procedure and/or XEN procedure combined with cataract surgery.

Abbreviations: IOP, intraocular pressure; POAG, primary open angle glaucoma; PEXG, pseudoexfoliative glaucoma.