Table 4.
Streptococcus canis isolated from mink—tentative ECOFFs and modes of MIC wildtype distribution, compared with modes and ECOFFs for S. pyogenes from EUCAST.
| Current study (mink) | EUCAST, S. pyogenes (mixed origins) | |||
|---|---|---|---|---|
| MODE | TECOFF | MODE | ECOFF | |
| Amoxicillin | –t | –t | 0.016 | 0.06 |
| Doxycycline | – | – | 0.12 | 0.5 |
| Spectinomycin | 16 | 32 | – | – |
| Tylosin | 0.12t | 0.25t, v | – | – |
| Lincomycin | 0.25 | 0.5 v | – | – |
| Sulfamethoxazole | 32 | 128 | – | – |
| Sulfa. + TMP | 0.06 | 0.12 | 0.12 | 0.5 |
All values are given as μg/mL. The MIC wildtype distributions were visually inspected and the tentative ECOFFs (TECOFFs) were suggested by nonlinear regression analysis using the ECOFFinder 2.0 software (4). Compared with data for S. pyogenes retrieved from EUCAST (13). t: truncated data, v: visually determined, Sulfa. + TMP: sulfamethoxazole in combination with trimethoprim (19:1).