Table 5.
Changes in Metabolic Parameters After Switching to Teneligliptin
| Parameters | Baseline | After Switching | Δ | P value |
|---|---|---|---|---|
| eGFR, mL/min/1.73m2 | 60.1 ± 24.9 | 58.6 ± 24.1 | −1.5 ± 11.7 | 0.109 |
| Total cholesterol, mg/dL* | 156.9 ± 37.4 | 152.7 ± 40.5 | −4.2 ± 41.8 | 0.128 |
| Triglycerides, mg/dL* | 148.8 ± 73.7 | 147.3 ± 70.0 | −1.5 ± 62.1 | 0.837 |
| HDL cholesterol, mg/dl* | 43.7 ± 12.8 | 43.7 ± 13.5 | 0.1 ± 13.1 | 0.951 |
| LDL cholesterol, mg/dl* | 85.6± 30.2 | 78.9 ± 32.7 | −6.6 ± 34.3 | 0.004 |
| AST, IU/L* | 25.4 ± 11.6 | 25.5 ±13.9 | 0.1 ± 11.8 | 0.475 |
| ALT, IU/L* | 23.7 ± 15.7 | 22.1 ± 14.6 | −1.6 ± 12.9 | 0.065 |
Notes: Data are presented mean ± SD. *log-transformed.
Abbreviations: eGFR, estimated glomerular filtration rate; HDL cholesterol, high-density lipoprotein cholesterol, LDL cholesterol; low-density lipoprotein cholesterol; AST, aspartate transaminase; ALT, alanine transferase.