TABLE 3.

Top 20 protein complexes enriched with HDFs

Complex ID	Complex name	No. of proteins	No. of HDFs	q value	No. of HIV targets
351	Spliceosome	143	81	2.50 × 10−49	52
1181	C complex spliceosome	80	46	4.62 × 10−28	35
193	PA700-20S-PA28 complex	36	28	2.13 × 10−22	20
181	26S proteasome	22	18	7.46 × 10−15	18
2825	BRCA1-RNA polymerase II complex	26	19	3.29 × 10−14	22
103	RNA polymerase II holoenzyme complex	24	18	7.88 × 10−14	22
2685	RNA polymerase II (RNAPII)	17	14	1.23 × 10−11	16
2755	17S U2 snRNP	33	19	1.29 × 10−11	15
32	PA700 complex	20	15	1.29 × 10−11	7
1332	Large Drosha complex	20	15	1.29 × 10−11	14
194	PA28gamma-20S proteasome	15	13	1.61 × 10−11	14
1183	CDC5L complex	30	18	1.61 × 10−11	14
2686	BRCA1-core RNA polymerase II complex	13	12	2.47 × 10−11	12
192	PA28-20S proteasome	16	13	6.56 × 10−11	13
191	20S proteasome	14	12	1.39 × 10−10	13
104	RNA polymerase II core complex	12	11	2.40 × 10−10	12
1335	SNW1 complex	18	12	1.87 × 10−8	12
728	CSA-POLIIa complex	13	10	5.72 × 10−8	11
3040	Multisynthetase complex	11	9	1.45 × 10−7	11
726	DDB2 complex	12	9	4.90 × 10−7	11