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. 2020 Nov 3;35(1):1953–1963. doi: 10.1080/14756366.2020.1835884

Table 3.

Inhibition of wild type and p66/p51C280A mutant HIV-1 RNase H activity by compounds 22 and 23.

Compound   IC50 (µM)
WT C280A
22 graphic file with name IENZ_A_1835884_ILG0023_B.gif 2.9 ± 0.89 0.61 ± 0.22
23 graphic file with name IENZ_A_1835884_ILG0024_B.gif 0.71 ± 0.03 1.2 ± 0.04