Table 4.
Biochemical data before and after therapy by herbal medicine, as well as relative changes of investigated mediators.
| Parameter | Before therapy (V1) (Mean ± SD) |
After therapy (V2) (Mean ± SD) |
p value | Relative changesa (Mean ± SD) |
|---|---|---|---|---|
| MCP-1 | 465.3 ± 314.1 | 598.3 ± 327.3 | .001 | 45.5 ± 54.8 |
| RANTES | 938.9 ± 1107.7 | 902.8 ± 1038.9 | .485 | −4.7 ± 38.1 |
| IP-10 | 199.8 ± 155.4 | 307.6 ± 179.4 | <.001 | 81.4 ± 80.5 |
| Eotaxin | 23.1 ± 37.8 | 26.5 ± 50.0 | .551 | 21.1 ± 90.7 |
| TARC | 10.9 ± 17.4 | 10.8 ± 19.5 | .937 | −17.3 ± 38.9 |
| MIP-1α | 703.6 ± 265.6 | 375.5 ± 166.8 | <.001 | −42.3 ± 26.0 |
| MIP-1β | 62.9 ± 31.4 | 73.0 ± 32.0 | .025 | 26.9 ± 49.0 |
| MIG | 0.5 ± 1.5 | 0.6 ± 1.7 | .917 | −11.5 ± 32.6 |
| MIP-3α | 56.6 ± 29.1 | 55.8 ± 26.9 | .603 | 7.7 ± 43.3 |
| ENA-78 | 335.6 ± 150.8 | 142.4 ± 98.8 | <.001 | −53.9 ± 25.4 |
| GROα | 153.1 ± 243.3 | 62.1 ± 114.4 | .005 | −20.3 ± 29.8 |
| I-TAC | 20.3 ± 33.4 | 17.4 ± 32.0 | .583 | −10.0 ± 41.2 |
| IL-8 | 589.8 ± 518.7 | 224.5 ± 157.6 | <.001 | −49.4 ± 34.0 |
The concentrations of inflammatory mediators are expressed in pg/mL.
aThe relative changes of investigated parameters: (value – baseline value)/baseline value.
Abbreviations. SD, standard deviation; V1, visit 1 (before treatment); V2, visit 2 (after treatment).