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. 2020 Sep 27;82(2):217–229. doi: 10.1002/ddr.21743

TABLE 2.

List of recent inhibitors against COVID‐19

Name Accession number Molecular weight (g/mol) Structure Mechanism of action
Darunavir DB01264 547.7 graphic file with name DDR-82-217-g022.jpg An inhibitor of HIV protease
Hydroxychloroquine DB01611 335.9 graphic file with name DDR-82-217-g018.jpg Inhibits antigen processing, and reduces the inflammatory response
Nelfinavir DB00220 567.8 graphic file with name DDR-82-217-g004.jpg A potent HIV‐1 protease inhibitor
Umifenovir DB13609 477.4 graphic file with name DDR-82-217-g012.jpg Direct virucidal effects and a host‐targeting agent (HTA)