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. 2020 Jul 18;6(3):100004. doi: 10.1016/j.jve.2020.100004

Table 2.

Virologic and immunologic characteristics of participants following treatment interruption, stratified by study arm.

Characteristics VHMa ​+ ​ARTb (N ​= ​9) ARTb only (N ​= ​5) p
Weeks from treatment interruption to viral load detection, ≥ 20 copies/mL
3 (2–5)
3.1 (3–11)
0.61
Viral load at detection, copies/mL
222 (33–41,822)
156 (52–395)
0.39
Weeks from treatment interruption to viral load rebound, >1,000 copies/mL
4 (2–7)
5 (4–16)
0.36
Peak viral load prior to ART resumption, copies/mL
10,797 (2,823–75,084)
4,717 (1,614–31,264)
0.21
Weeks from viral load detection, ≥20 copies/mL, to ART resumption
1 (0.1–4.1)
2 (1–5.3)
0.22
Weeks from ART resumption to VL suppression, <20 copies/mL
2.9 (0.9–10.9)
2 (1.9–3.9)
0.29
CD4+ T cells/μL change from study entry to ARTb resumption 2 (−376 to 549) 16 (−284 to 474) 0.74

Data are presented as Median (Minimum-Maximum).

a

VHM: vorinostat/hydroxychloroquine/maraviroc.

b

ART: antiretroviral therapy.