Table 2.
Characteristics | VHMa + ARTb (N = 9) | ARTb only (N = 5) | p |
---|---|---|---|
Weeks from treatment interruption to viral load detection, ≥ 20 copies/mL |
3 (2–5) |
3.1 (3–11) |
0.61 |
Viral load at detection, copies/mL |
222 (33–41,822) |
156 (52–395) |
0.39 |
Weeks from treatment interruption to viral load rebound, >1,000 copies/mL |
4 (2–7) |
5 (4–16) |
0.36 |
Peak viral load prior to ART resumption, copies/mL |
10,797 (2,823–75,084) |
4,717 (1,614–31,264) |
0.21 |
Weeks from viral load detection, ≥20 copies/mL, to ART resumption |
1 (0.1–4.1) |
2 (1–5.3) |
0.22 |
Weeks from ART resumption to VL suppression, <20 copies/mL |
2.9 (0.9–10.9) |
2 (1.9–3.9) |
0.29 |
CD4+ T cells/μL change from study entry to ARTb resumption | 2 (−376 to 549) | 16 (−284 to 474) | 0.74 |
Data are presented as Median (Minimum-Maximum).
VHM: vorinostat/hydroxychloroquine/maraviroc.
ART: antiretroviral therapy.