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. 2020 Oct 15;20(6):227. doi: 10.3892/etm.2020.9357

Figure 4.

Figure 4

miR-124 inhibits STAT3 activation. (A) TargetScan software identified the complementary gene sequences between miRNA-124 and the 3'-UTR of STAT3. (B) The dual-luciferase reporter assay detected relative luciferase activities. (C) Western blotting was performed to measure the relative expression levels of p-STAT3 and total STAT3 in the sham, NC and agomiRNA-124 groups. $P<0.05 vs. NC, #P<0.05 vs. sham, ***P<0.001. miR, microRNA; 3'UTR, 3'-untranslated region; p, phosphorylated; NC, negative control; WT, wild-type; Mut, mutant.