Table III.
Changes and roles of cytokines at the pathological level.
| Clinical category | Molecular pathology | Impact | Change |
|---|---|---|---|
| Menstrual pain | PGF2a | Acceleration of endometrial contraction | Increased |
| CPAF | Aggravation of anoxia | Increased | |
| Abnormal uterine bleeding | Follistatin | Promotion of repair | Decreased |
| DuP-697/indomethacin | Suppression of menstruation | Decreased | |
| Cox-2 | Inflammatory response | Increased | |
| Endometriosis | CXCR7 | Induction of endometriosis | Increased |
| K:F9 | Promotion of activity | Increased | |
| KLF13 | Participation in the pathological process | Decreased | |
| TFF3 | Differential marker | Increased | |
| Iron deposit | Erythrocytosis/excess iron storage | Increased | |
| Successful embro implantation | ESC decidua | Secretion of factors | Increased |
| poFUT1 | Promotion of endometrial decentralization | Increased | |
| TRP | Embryo implantation | Increased | |
| Tiam1 | Regulation of decidua | Increased | |
| Omega-3 | Facilitation of embryo implantation | Increased | |
| MSX1 | Control of embryonic development | Increased |
PGF1a, prostaglandin F2α; CPAF, carbamyl PAF; Cox-2, cyclooxygenase-2; KLF13, Krüppel-like factor; TFF3, three-leaf factor 3; ESC, endometrial stromal cells; poFUT1, protein o-fucosylation; TRP, transient receptor potential.