Table 4.
Sensitivity and specificity of RDT between study sites using microscopy and qPCR as gold standard, Assosa zone, northwest Ethiopia, November to December 2018
| PfHRP2 RDT against microscopy | PfLDH RDT against microscopy | PfHRP2 RDT against qPCR | PfLDH RDT against qPCR | |||||
|---|---|---|---|---|---|---|---|---|
| Value | 95% CI | Value | 95% CI | Value | 95% CI | Value | 95% CI | |
| Rural (n = 260) | ||||||||
| Sensitivity | 96 | (88, 99) | 82 | (71, 89) | 95 | (88, 98) | 67 | (57, 77) |
| Specificity | 94 | (89, 96) | 98 | (95, 99) | 99 | (97, 100) | 97 | (94, 99) |
| Semi-urban (n = 146) | ||||||||
| Sensitivity | 94 | (82, 98) | 97 | (86, 99) | 93 | (82, 98) | 61 | (48, 73) |
| Specificity | 92 | (85, 96) | 98 | (94, 100) | 97 | (91, 99) | 96 | (89, 98) |
PfHRP2 = Plasmodium falciparum histidine-rich protein 2; PfLDH = Plasmodium falciparum lactate dehydrogenase; qPCR = quantitative PCR; RDT = rapid diagnostic test.