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. 2020 Oct 6;22(6):4637–4644. doi: 10.3892/mmr.2020.11566

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Copyright: © Guo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Identification and validation of differentially expressed hub lncRNAs associated with HCM. (A) Volcano plot. A total of 80 downregulated and 210 upregulated lncRNAs were identified using the Limma package. (B) Heatmap. Differentially expressed lncRNAs were identified in the HCM groups relative to the controls. Each lncRNA was assigned a color according to Z-score scale. (C) Venn diagram. Differentially expressed hub lncRNAs were obtained by mapping hub lncRNAs against differentially expressed lncRNAs. HCM, hypertrophic cardiomyopathy; FC, fold-change; adj.P, P-value after Benjamini-Hochberg adjustment; lncRNA, long noncoding RNA.