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NOB pre-treatment reduces renal damage. (A) Cr levels in serum (µmol/l). (B) BUN levels in serum (mmol/l). (C) Tubular injury scores. (D) Renal tissue H&E staining. Magnification, ×200. Scale bar, 20 µm. n=3. *P<0.05, **P<0.01, ****P<0.0001. NOB, nobiletin; Cr, creatinine; I/R, ischemia/reperfusion; BUN, blood urea nitrogen; CHOP, C/EBP homologous protein.
