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ATG reduces oxidative stress in BLM-induced skin fibrosis model mice. (A) The levels of GSH, SOD and MDA were detected spectrophotometrically in skin tissue homogenate supernatants. (B) Nrf2 (nuclear) and HO-1 protein expression levels were measured via western blotting. *P<0.05 and **P<0.01. ATG, arctigenin; BLM, bleomycin; GSH, glutathione; SOD, superoxide dismutase; MDA, malondialdehyde; Nrf2, nuclear factor erythroid-2-related factor 2; HO-1, heme oxygenase-1; Con, control.
