Table 3.
Comparison of model results with the best results reported by similar studies
Article | Network approach | Model | Chem. | Bio. | Other | Acc | Sens | PPV | AUROC | |
---|---|---|---|---|---|---|---|---|---|---|
Liu et al.24 | No | SVM | Yes | Yes | Yes | 0.967 | 0.631 | 0.662 | 0.952 | |
Huang et al.23 | No | SVM | Yes | Yes | No | NR | NR | NR | 0.760 | |
Cami et al.21 | Yes | LR | Yes | No | Yes | NR | 0.608 | NR | 0.869 | |
Huang et al.25 | No | SVM | No | Yes | No | 0.675 | 0.632 | NR | 0.771 | |
Present study | Yes | GBT | No | Yes | No | 0.928 | 0.728 | 0.769 | 0.916 |
Chem. indicates whether chemical features of drugs are used for ADE prediction. *Bio. indicates whether biological features of drugs are used for ADE prediction. *Other indicates whether other features (eg, taxonomical, phenotypical, etc.) of drugs are used for ADE prediction.